Phase I: Overview
Accelerating the transition of new tuberculosis drug combinations from Phase II to Phase III trials: New technologies and innovative designs | PLOS Medicine
Single- and Multiple-Ascending-Dose Study of the Safety, Tolerability, and Pharmacokinetics of the Polymyxin Derivative SPR206 | Antimicrobial Agents and Chemotherapy
Study design. Part 1: single ascending dose cohorts in healthy... | Download Scientific Diagram
Pharmacokinetics, Safety and Tolerability of the HCV Polymerase Inhibitor ABT-333 Following Multiple Ascending Doses and Effect of Co-Administration of Ketoconazole in Healthy Subjects
The phases of preclinical and clinical trials
A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis | Gut
Patient disposition. SAD single ascending dose, MAD multiple ascending... | Download Scientific Diagram
CR TidBit – Single Ascending Dose to Multiple Ascending Dose. | AuroBlog | Clinical Research Blog | Aurous HealthCare CRO, India
JCI - Monoclonal antibody targeting BDCA2 ameliorates skin lesions in systemic lupus erythematosus
Pharmacokinetics of ASP4345 from Single Ascending-Dose and Multiple Ascending-Dose Phase I Studies | SpringerLink
Single- and Multiple-Ascending-Dose Study of the Safety, Tolerability, and Pharmacokinetics of the Polymyxin Derivative SPR206 | Antimicrobial Agents and Chemotherapy
Safety, pharmacokinetics, and antimalarial activity of the novel plasmodium eukaryotic translation elongation factor 2 inhibitor M5717: a first-in-human, randomised, placebo-controlled, double-blind, single ascending dose study and volunteer infection ...
A First‐in‐Human Phase 1 Randomized Single and Multiple Ascending Dose Study of RPh201 in Healthy Volunteers - Hazan - 2020 - Clinical Pharmacology in Drug Development - Wiley Online Library
Phase 1a Randomized Double-Blind Placebo-Controlled Single-Ascending Dose and Multiple-Ascending Dose Studies of Orally Inhaled GB002 in Healthy Adult Subjects - Gossamer Bio
Schematic of the ECG timepoints and meals in the single-ascending dose... | Download Scientific Diagram
Study design: (A) single ascending dose; (B) multiple ascending dose. | Download Scientific Diagram
ONCE-DAILY REGIMENS OF THE HCV NS3/4A-PROTEASE INHIBITOR TMC435350 ARE PREDICTED TO PROVIDE THERAPEUTIC EXPOSURE IN PLASMA AND LIVER
Single and multiple ascending dose GS-9256 and GS-9451 clinical trial... | Download Scientific Diagram
Traditional Process First in Human Single Ascending Dose Multiple Ascending Dose U.S.A. Japan Phase II Phase III NDA in Japan Phase II Phase III NDA in. - ppt download
Phase I Trial of Anti–Vascular Endothelial Growth Factor/Anti-angiopoietin 2 Bispecific Antibody RG7716 for Neovascular Age-Related Macular Degeneration - ScienceDirect
Planning Your (First) First-in Human Trial? Considerations for Success - Xtalks
On Biostatistics and Clinical Trials: SAD and MAD: Single Ascending Dose and Multiple Ascending Dose first-in-human studies
