Cancers | Free Full-Text | Rapid Progress in the Use of Immunomodulatory Drugs and Cereblon E3 Ligase Modulators in the Treatment of Multiple Myeloma
Controversy regarding the functional conservation of cereblon CUL4-type E3 ligase substrate receptor
Mechanism of action of CRL4 CRBN E3 ubiquitin ligase and its effects... | Download Scientific Diagram
CRBN Archives - Network of Cancer Research
Exploiting ubiquitin ligase cereblon as a target for small-molecule compounds in medicine and chemical biology - ScienceDirect
Cancers | Free Full-Text | Rapid Progress in the Use of Immunomodulatory Drugs and Cereblon E3 Ligase Modulators in the Treatment of Multiple Myeloma
CME: Mezigdomide (CC-92480), a Potent, Novel Cereblon E3 Ligase Modulator, Combined With Dexamethasone in Patients With Relapsed/Refractory Multiple Myeloma: Preliminary Results From the Dose-Expansion Phase of the CC-92480-MM-001 Trial Medical ...
Positive selection of cereblon modified function including its E3 ubiquitin ligase activity and binding efficiency with AMPK - ScienceDirect
Cereblon: promise and challenges for combating human diseases | SpringerLink
Cereblon E3 Ligase Modulators – BMS
Key regulators of sensitivity to immunomodulatory drugs in cancer treatment | Biomarker Research | Full Text
A Cell-Based Target Engagement Assay for the Identification of Cereblon E3 Ubiquitin Ligase Ligands and Their Application in HDAC6 Degraders - ScienceDirect
Molecules | Free Full-Text | Inducing the Degradation of Disease-Related Proteins Using Heterobifunctional Molecules
SALL4 mediates teratogenicity as a thalidomide-dependent cereblon substrate | Nature Chemical Biology
Molecular mechanism of action of cereblon E3 ligase modulators in... | Download Scientific Diagram
A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase | Nature
A Cereblon Modulator CC-885 Induces CRBN- and p97-Dependent PLK1 Degradation and Synergizes with Volasertib to Suppress Lung Cancer: Molecular Therapy - Oncolytics
Single subunit degradation of WIZ, a lenalidomide- and pomalidomide-dependent substrate of E3 ubiquitin ligase CRL4CRBN | bioRxiv
Single subunit degradation of WIZ, a lenalidomide- and pomalidomide-dependent substrate of E3 ubiquitin ligase CRL4CRBN | bioRxiv
CC-90009: A Cereblon E3 Ligase Modulating Drug That Promotes Selective Degradation of GSPT1 for the Treatment of Acute Myeloid Leukemia | Journal of Medicinal Chemistry
Cancers | Free Full-Text | CRL4CRBN E3 Ligase Complex as a Therapeutic Target in Multiple Myeloma
Frontiers | Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine
